adalimumab vs theophylline

According to this portal's Publishing Organization, this page was last reviewed in August 2026 against our methodology. Figures and extracts on this site, including tables above 1,000 rows when the corpus is that large, are the publisher's responsibility.

Side-by-side comparison of adalimumab and theophylline. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

Upon initiation or discontinuation of IDACIO in patients being treated with CYP450 substrates with a narrow therapeutic index, monitoring of the effect (e.g., warfarin) or drug concentration (e.g., cyclosporine or theophylline) is recommended and the individual dose of the drug product may be adjusted as needed.

Drug Class
adalimumab TNF-Alpha Inhibitor (Biologic)
theophylline Methylxanthine Bronchodilator
Type
adalimumab Prescription
theophylline Prescription
Summary
adalimumab

Idacio is a medicine that blocks a protein called TNF. It is used to treat several diseases, including arthritis and Crohn's disease.

theophylline

Theophylline is a medicine that helps you breathe easier. It treats the symptoms of asthma and other lung problems.

What It Treats
adalimumab

Idacio can help adults with rheumatoid arthritis by reducing joint pain and damage. It can also help children (2 years and older) with juvenile idiopathic arthritis. Idacio treats psoriatic arthritis, ankylosing spondylitis, Crohn’s disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa and uveitis.

theophylline

Theophylline treats the symptoms of long-term asthma and other lung diseases. These include emphysema and chronic bronchitis, which make it hard to breathe. This medicine helps to open up your airways so you can breathe easier.

How It Works
adalimumab

Idacio works by blocking a protein in your body called tumor necrosis factor (TNF). TNF can cause inflammation and damage in certain diseases. By blocking TNF, Idacio can reduce these symptoms.

theophylline

Theophylline is a bronchodilator. It works by relaxing the muscles in your airways. This allows more air to flow in and out of your lungs.

Common Side Effects
adalimumab
  • Infections (like colds or sinus infections)
  • Injection site reactions (redness, itching, pain, or swelling)
  • Headache
  • Rash
theophylline
  • Nausea
  • Vomiting
  • Headache
  • Trouble sleeping (insomnia)
FAERS Reports
adalimumab
  • Pain 49,062
  • Arthralgia 48,039
  • Injection Site Pain 47,251
  • Fatigue 39,111
  • Rheumatoid Arthritis 35,573
theophylline
  • Dyspnoea 2,273
  • Asthma 1,942
  • Pneumonia 1,318
  • Wheezing 1,306
  • Vomiting 1,101
Serious Warnings
adalimumab

Idacio can increase your risk of serious infections that could lead to hospitalization or death. Tell your doctor if you have any infections before starting Idacio. Idacio may also increase your risk of certain cancers, including lymphoma. Children and teens taking TNF blockers like Idacio have developed rare, aggressive cancers.

theophylline

If your theophylline levels get too high in your blood, it can cause serious side effects. These include severe vomiting, irregular heartbeats, and seizures. These can be life-threatening.

Pregnancy
adalimumab

Tell your doctor if you are pregnant or plan to become pregnant. Idacio can cross the placenta and may affect your baby's immune system. Talk to your doctor about vaccines for your baby if you took Idacio during pregnancy.

theophylline

It is not known if theophylline can harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is also not known if theophylline passes into breast milk, so talk to your doctor if you are breastfeeding.

Also Compare, Nearby Drugs

How to Read This adalimumab vs theophylline Comparison

adalimumab is classified in the TNF-Alpha Inhibitor (Biologic) drug class, while theophylline sits within the Methylxanthine Bronchodilator class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, adalimumab has 219,036 submissions while theophylline has 7,940. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to this medicine can affect the way your body processes theophylline, which might lead to levels that are too high or too low.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for adalimumab or theophylline.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.