aclidinium vs montelukast
Side-by-side comparison of aclidinium and montelukast Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
Tudorza Pressair
Singulair
Duaklir Pressair is a combination medicine used to help people with COPD breathe better. It contains two medicines that open up the airways in your lungs.
Montelukast is a medicine that helps control asthma and allergies. It works by blocking certain natural substances in your body that cause asthma and allergy symptoms.
Duaklir Pressair is used to treat chronic obstructive pulmonary disease (COPD). COPD is a long-term lung disease that makes it hard to breathe. This medicine helps to open the airways and make it easier to breathe for people with COPD.
Montelukast is used to prevent asthma symptoms and treat long-term asthma. It can also prevent breathing problems caused by exercise. Additionally, it helps relieve symptoms of allergies like sneezing, runny nose, and itchy eyes, both seasonal and year-round.
Duaklir Pressair contains two medicines that work in different ways. One medicine relaxes the muscles around your airways, opening them up. The other medicine prevents the muscles from tightening.
This medicine blocks leukotrienes, which are substances your body releases that cause swelling in the lungs and tightening of the muscles around your airways. By blocking these substances, montelukast helps you breathe easier. It also reduces allergy symptoms.
- • Upper respiratory infection
- • Headache
- • Back pain
- • Upper respiratory infection
- • Fever
- • Headache
- • Sore throat
- • Cough
- Difficulty breathing 1,869
- Inhaler not working correctly 1,281
- Skipped a dose of medicine 1,017
- Asthma 814
- Chronic obstructive pulmonary disease (COPD) 764
- Difficulty breathing 7,724
- Asthma 7,439
- Medicine not working 5,931
- Tiredness 5,505
- Headache 4,785
LABAs, such as formoterol fumarate, one of the active ingredients in DUAKLIR PRESSAIR, increase the risk of asthma-related death. Duaklir Pressair is not for asthma. Do not use Duaklir Pressair if you are allergic to milk proteins or any of the ingredients in it. Tell your doctor if you have heart problems, glaucoma, trouble urinating, diabetes, or seizures.
Do not use montelukast to treat a sudden asthma attack. Always have your rescue medicine with you. Do not suddenly stop taking steroid medicines if you are also taking montelukast. Some patients have experienced changes in behavior or mood, including suicidal thoughts. Tell your doctor right away if you notice these changes.
It is not known if Duaklir Pressair will harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is also not known if this medicine passes into breast milk. Talk to your doctor about the best way to feed your baby if you are taking Duaklir Pressair.
If you are pregnant, talk to your doctor before taking montelukast. It is not known if montelukast passes into breast milk, so talk to your doctor if you are breastfeeding.
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How to Read This aclidinium vs montelukast Comparison
aclidinium is classified in the Long-Acting Muscarinic Antagonist (LAMA) drug class, while montelukast sits within the Leukotriene Receptor Antagonist class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, aclidinium has 5,745 submissions while montelukast has 31,384. Those figures reflect cumulative reporting volume — not per-patient risk — so older, widely dispensed drugs typically look worse on count alone. No direct interaction between these two drugs is listed in our FDA-derived dataset, though co-prescription still warrants pharmacist review. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between aclidinium and montelukast — always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.