Alternatives to venlafaxine
3 same-class SPL records vs venlafaxine - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.
Brand: Effexor, Effexor XR
How to read a high-report FAERS peer set
venlafaxine ranks in the upper FAERS-volume third of the corpus (#108 of 524); 3 same-class peers are listed for field comparison only. Labeled indication field for venlafaxine: Venlafaxine is used to treat major depressive disorder.
Top FAERS reaction fields for venlafaxine total 33,772 reports across 10 reactions, set beside desvenlafaxine, duloxetine, levomilnacipran. Counts are exposure-weighted submissions, not per-patient risk.
About venlafaxine
Venlafaxine is a medication used to treat depression. It helps to improve your mood by affecting certain chemicals in the brain.
Used for: Venlafaxine is used to treat major depressive disorder. This condition can cause a persistent feeling of sadness or loss of interest in daily activities. It may also help maintain improvement in patients with recurrent depression.
3 Serotonin-Norepinephrine Reuptake Inhibitor (SNRI) peers (wide set)
desvenlafaxine
RxPristiq
Pristiq is used to treat major depressive disorder (MDD) in adults. MDD can cause you to feel sad, lose interest in activities, and have trouble with daily life. This medicine can help improve your mood and energy levels.
duloxetine
RxCymbalta
Duloxetine can treat major depressive disorder and generalized anxiety disorder in adults and children (7 years and older). It can also treat diabetic nerve pain, fibromyalgia, and chronic muscle or bone pain in adults. In children, it can treat fibromyalgia (13 years and older).
levomilnacipran
RxFetzima
Fetzima is used to treat major depressive disorder (MDD) in adults. MDD can cause you to feel sad, lose interest in activities, and have trouble with daily life. Fetzima can help improve your mood and reduce these symptoms.
venlafaxine vs desvenlafaxine & duloxetine · FAERS reaction fields
FAERS top-reaction field "Toxicity To Various Agents" shows the widest count spread between venlafaxine and desvenlafaxine, duloxetine, levomilnacipran in this extract (2,053-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | venlafaxine | desvenlafaxine | duloxetine | levomilnacipran |
|---|---|---|---|---|
| Nausea | 4,298 | 206 | 4,782 | 143 |
| Toxicity To Various Agents | 4,265 | 233 | 2,212 | - |
| Fatigue | 4,198 | 166 | 4,787 | - |
| Headache | 3,740 | 159 | 3,654 | 112 |
| Completed Suicide | 3,169 | 186 | 2,079 | - |
| Drug Interaction | 3,114 | 164 | 2,063 | - |
| Dizziness | 3,026 | 133 | 3,034 | 106 |
| Diarrhoea | 2,786 | 94 | 3,262 | - |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
venlafaxine FAERS volume vs class peers
FAERS volume band
venlafaxine is FAERS corpus rank #108 of 524 (high volume tercile). Top-reaction field total: 33,772.
Frequently Asked Questions
Where does venlafaxine sit in FAERS report volume vs Serotonin-Norepinephrine Reuptake Inhibitor (SNRI) peers? ▼
Registry note: FAERS counts are voluntary reports and do not establish causation or risk rates. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for venlafaxine: see also the generic vs brand label guide when reading Effexor SPL strings.
Read our methodology - how this data is sourced, computed, and verified.