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Medicines labeled for the same conditions

Alternatives to risankizumab

11 other medicines are given the same way (subcutaneous) and in the same FDA class as risankizumab or labeled mainly for the same use (psoriasis); 5 are in its class, interleukin-23 antagonists: ustekinumab, ustekinumab-aekn, guselkumab, ustekinumab-srlf and 1 more; the others include 2 interleukin-17a antagonists, 1 interleukin-36 receptor antagonist and 1 interleukin-17 receptor a antagonist (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $14,728.91 per mL (Tremfya 100 mg/mL syringe) (what pharmacies paid in the NADAC survey; strengths differ).

Which medicines are labeled for the same conditions as risankizumab?

Psoriasis lists all 38 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (subcutaneous)Pharmacy costBoxed warningShortage
Risankizumabinterleukin-23 antagonistthis medicinenone listed$22,774.36 per mL 150 mg/mL penNoNo current entry
Ustekinumabinterleukin-12 antagonist · same classCrohn's disease and ulcerative colitisnone listed$29,874.45 per mL 45 mg/0.5 mL syringeNoNo current entry
Ustekinumab-aekninterleukin-12 antagonist · same classCrohn's disease and ulcerative colitisnone listedn/aNoNo current entry
Guselkumabinterleukin-23 antagonist · same classCrohn's disease and ulcerative colitisnone listed$14,728.91 per mL 100 mg/mL syringeNoNo current entry
Ustekinumab-srlfinterleukin-12 antagonist · same classCrohn's disease and ulcerative colitisnone listedn/aNoNo current entry
Tildrakizumabinterleukin-23 antagonist · same classPsoriasisnone listedn/aNoNo current entry
Adalimumab-ryvkCrohn's disease and ulcerative colitis, Psoriasisnone listed$499.12 per unit 40 mg/0.4 mL autoinjectorYesA presentation being discontinued
BimekizumabPsoriasisnone listed$8,073.83 per mL 160 mg/mL autoinjectorNoNo current entry
Ixekizumabinterleukin-17a antagonistPsoriasisnone listed$7,370.72 per mL 80 mg/mL autoinjectorNoNo current entry
Secukinumabinterleukin-17a antagonistPsoriasisnone listed$3,946.35 per mL 300 mg dose/2 pens (150 mg/pen)NoNo current entry
Spesolimabinterleukin-36 receptor antagonistPsoriasisnone listedn/aNoNo current entry
Brodalumabinterleukin-17 receptor a antagonistPsoriasisnone listedn/aYesNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Risankizumab: the full record
label, generics, price, shortages, recalls
Risankizumab vs ustekinumab
two records side by side
Guselkumab vs risankizumab
two records side by side