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Medicines labeled for the same conditions

Alternatives to polyethylene glycol 3350

16 other medicines are given the same way (oral) and in the same FDA class as polyethylene glycol 3350 or labeled mainly for the same use (constipation); 3 are in its class, osmotic laxatives: magnesium sulfate, lactulose and sodium phosphate dibasic and sodium phosphate monobasic; the others include 1 chloride channel activator and 1 serotonin-4 receptor agonist (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.0039 per gram (Epsom salt) (what pharmacies paid in the NADAC survey; strengths differ).

Which medicines are labeled for the same conditions as polyethylene glycol 3350?

Constipation lists all 20 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (oral)Pharmacy costBoxed warningShortage
Polyethylene glycol 3350osmotic laxativethis medicine73 labelers$0.0286 per gram 3350 powdNoNo current entry
Magnesium sulfatecalculi dissolution agent · same classConstipationnone listed$0.0039 per gram Epsom saltNoNo current entry
Lactuloseosmotic laxative · same classConstipation22 labelers$8.22 per packet 10 g packetNoNo current entry
Sodium phosphate dibasic and sodium phosphate monobasicosmotic laxative · same classConstipation1 labelern/aNoNo current entry
DocusateConstipationnone listed$0.0276 per unit 100 mg softgelNoNo current entry
SennosidesConstipationnone listed$0.0258 per tablet 8.6 mg tabletNoNo current entry
BisacodylConstipationnone listed$0.0441 per tablet 5 mg tabletNoNo current entry
Magnesium hydroxideConstipationnone listed$0.0095 per mL Milk of magnesia suspensionNoNo current entry
Magnesium citrateConstipationnone listed$0.0066 per mL Magnesium citrate solutionNoNo current entry
Lubiprostonechloride channel activatorConstipation10 labelers$0.651 per capsule 24 mcg capsuleNoNo current entry
Prucaloprideserotonin-4 receptor agonistConstipation18 labelers$0.639 per tablet 1 mg tabletNoNo current entry
Psyllium huskConstipationnone listedn/aNoNo current entry
Calcium polycarbophilConstipationnone listed$0.0591 per unit 625 mg capletNoNo current entry
Mineral oilConstipationnone listed$0.0099 per mL Mineral oilNoNo current entry
Castor oilConstipationnone listed$0.0193 per mL Castor oilNoNo current entry
MethylcelluloseConstipationnone listed$0.0135 per gram Fiber therapy powderNoNo current entry
Polyethylene glycol 3500Constipation1 labelern/aNoNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Polyethylene glycol 3350: the full record
label, generics, price, shortages, recalls