Medicines labeled for the same conditions
Alternatives to edoxaban
4 other medicines are given the same way (oral) and in the same FDA class as edoxaban or labeled mainly for the same use (atrial fibrillation); 2 are in its class, factor Xa inhibitors: rivaroxaban and apixaban; the others include 1 vitamin k antagonist and 1 direct thrombin inhibitor (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.650 per rivaroxaban 2.5 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as edoxaban?
Atrial fibrillation lists all 17 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Edoxabanfactor Xa inhibitor | this medicine | none listed | $15.51 per tablet 60 mg tablet | Yes | No current entry |
| Rivaroxabanfactor Xa inhibitor · same class | Atrial fibrillation, Blood clots (DVT and PE), Stroke prevention | 20 labelers | $0.650 per tablet 2.5 mg tablet | Yes | A presentation being discontinued |
| Apixabanfactor Xa inhibitor · same class | Atrial fibrillation, Blood clots (DVT and PE), Stroke prevention | 2 labelers | $5.52 per tablet 5 mg tablet | Yes | No current entry |
| Warfarinvitamin k antagonist | Atrial fibrillation, Blood clots (DVT and PE) | 19 labelers | $0.093 per tablet 2 mg tablet | Yes | No current entry |
| Dabigatrandirect thrombin inhibitor | Atrial fibrillation, Blood clots (DVT and PE), Stroke prevention | 16 labelers | $0.795 per capsule 150 mg capsule | Yes | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Edoxaban: the full record
- label, generics, price, shortages, recalls
- Edoxaban vs rivaroxaban
- two records side by side