Prescription and over-the-counter medicine
Ascorbic acid Brand names: Ascor
Ascorbic acid (Ascor) is a prescription and over-the-counter medicine with an FDA approval on record since 2017. FDA's NDC Directory lists it from 4 generic labelers.
- Generic listed
Check it at the source: the ascorbic acid FDA label on DailyMed (effective May 29, 2026, McGuff Pharmaceuticals, Inc.); the NDA 209112 record on Drugs@FDA; every ascorbic acid label on DailyMed.
Highlights of the record
FDA label of May 29, 2026; NDC Directory, Drugs@FDA and Orange Book, October 8, 2026
Used for
From the label: indications and usageINDICATIONS AND USAGE ASCOR is vitamin C indicated for the short term (up to 1 week) treatment of scurvy in adult and pediatric patients age 5 months and older for whom oral administration is not possible, insufficient or contraindicated.
Forms and strengths
- 500 mg/ml
Injection.
On the market
- Earliest approval on file
- October 2, 2017 Ascor, Mcguff; Drugs@FDA’s file, where older or withdrawn approvals can be missing
- Generic approvals
- 3 first August 7, 2025; 3 with a marketed status in Drugs@FDA
- Labelers listed (NDC)
- 5 of which 4 under generic applications, 1 under brand applications, repackagers included; 2 more under the over-the-counter monograph, without an application
Supply and safety
- Pharmacy cost (NADAC)
- Not in the survey
- Shortage (FDA)
- No current entry
- Recalls by its makers (FDA)
- 4 since 2012 2 Class I among all firms' recalls; latest July 30, 2025; 36 more by firms not listed as its makers
- FAERS reports
- 23,122 through July 30, 2026
What is ascorbic acid used for?
From the label: indications and usageINDICATIONS AND USAGE ASCOR is vitamin C indicated for the short term (up to 1 week) treatment of scurvy in adult and pediatric patients age 5 months and older for whom oral administration is not possible, insufficient or contraindicated. Limitations of Use ASCOR is not indicated for treatment of vitamin C deficiency that is not associated with signs and symptoms of scurvy. ASCOR is vitamin C indicated for the short term (up to 1 week) treatment of scurvy in adult and pediatric patients age 5 months and older for whom oral administration is not possible, insufficient or contraindicated. […]
FDA pharmacologic class: Vitamin C.
Source: FDA drug label (Ascor), McGuff Pharmaceuticals, Inc., effective May 29, 2026 (SPL set 388aad52-fc01-4784-9791-1dbc80c69306), via openFDA; the full label on DailyMed
Is there a generic for ascorbic acid (Ascor)?
The FDA approved the first generic ascorbic acid on August 7, 2025. 3 generic applications are approved; 3 of them carry a current (not discontinued) marketing status in Drugs@FDA; that status is not evidence that the generic is on sale.
FDA's NDC Directory lists ascorbic acid from 4 labelers under a generic (ANDA) application and from 1 brand labeler. A listing means the company has registered the product for sale; it does not show that every pharmacy stocks it.
- 2017 earliest approval on file
- 2025 first generic approved
- red ticks recalls
Source: Drugs@FDA, FDA NDC Directory and the Orange Book (openFDA bulk files, October 8, 2026)
Has ascorbic acid been recalled?
The FDA's Enforcement Report lists 40 recalls naming ascorbic acid since 2012: 2 Class I (the most serious), 38 Class II, 0 Class III; 4 still ongoing. 36 of them are by firms that FDA's NDC Directory does not list as a maker of ascorbic acid and that hold no application for it in Drugs@FDA, such as compounding pharmacies or bulk-ingredient suppliers; the recall notice names the product recalled. A recall names products and lots, not every product of the medicine.
| Started | Class | Company | Reason |
|---|---|---|---|
| July 30, 2025 | Class II | GenoGenix LLC | Lack of Assurance of Sterility |
| March 7, 2022 | Class II | TMC Acquisition LLC dba Tailor Made Compounding not a listed maker | Lack of Assurance of Sterility |
| November 17, 2021 | Class II | ASP CARES not a listed maker | Lack of Assurance of Sterility |
| August 13, 2021 | Class II | First Royal Care Co. LLC, dba Red Mountain Compounding … not a listed maker | Lack of Assurance of Sterility: FDA inspection raised sterility assurance concerns |
| September 12, 2019 | Class II | KRS Global Biotechnology, Inc not a listed maker | Lack of Assurance of Sterility |
| August 28, 2019 | Class II | Atlas Pharmaceuticals, LLC not a listed maker | Labeling: Not Elsewhere Classified; product is labeled as "Non-Corn Source" however the product is from a corn source. |
| June 19, 2019 | Class II | RXQ Compounding LLC not a listed maker | Crystallization |
| December 17, 2018 | Class II | Promise Pharmacy, LLC not a listed maker | Lack of sterility assurance. |
Source: FDA Enforcement Report (drug recalls) via openFDA, through October 8, 2026
What does the ascorbic acid label say about other medicines?
The ascorbic acid label names 9 other medicines in its interaction, contraindication or warning sections. The labels of 19 other medicines name ascorbic acid. The sentences are the labels' own; a label lists what its studies and reports found, not every interaction.
| Medicine named | Section | What the label says |
|---|---|---|
| Amphetamine | drug interactions | Bleomycin is inactivated in vitro by ascorbic acid (7.1). Amphetamine and Other Drugs Affected by Urine Acidification: Ascorbic acid may cause acidification of the urine and result in decreased amphetamine serum levels affect excretion and plasma concentrations of other drugs sensitive to urine pH (7.2). … |
| Bleomycin | drug interactions | Bleomycin is inactivated in vitro by ascorbic acid (7.1). Amphetamine and Other Drugs Affected by Urine Acidification: Ascorbic acid may cause acidification of the urine and result in decreased amphetamine serum levels affect excretion and plasma concentrations of other drugs sensitive to urine pH (7.2). … |
| Cysteine | warnings and precautions | Acidification of the urine by ascorbic acid may cause precipitation of cysteine, urate or oxalate stones. |
| Doxycycline | drug interactions | DRUG INTERACTIONS Antibiotics: Ascorbic acid may decrease the activities of erythromycin, kanamycin, streptomycin, doxycycline, and lincomycin. |
| Erythromycin | drug interactions | DRUG INTERACTIONS Antibiotics: Ascorbic acid may decrease the activities of erythromycin, kanamycin, streptomycin, doxycycline, and lincomycin. |
| Fluphenazine | drug interactions | It has been reported that concurrent administration of ascorbic acid and fluphenazine has resulted in decreased fluphenazine plasma concentrations. |
| Lincomycin | drug interactions | DRUG INTERACTIONS Antibiotics: Ascorbic acid may decrease the activities of erythromycin, kanamycin, streptomycin, doxycycline, and lincomycin. |
| Streptomycin | drug interactions | DRUG INTERACTIONS Antibiotics: Ascorbic acid may decrease the activities of erythromycin, kanamycin, streptomycin, doxycycline, and lincomycin. |
| Warfarin | drug interactions | … amphetamine serum levels affect excretion and plasma concentrations of other drugs sensitive to urine pH (7.2). Warfarin: Continue standard monitoring (7.3) See 17 for PATIENT COUNSELING INFORMATION Antibiotics: Ascorbic acid may decrease the activities of erythromycin, kanamycin, streptomycin, doxycycline, and … |
Other labels that name ascorbic acid
- Alpha-tocopherol, asorbic acid and 11 other ingredients
- Drospirenone and ethinyl estradiol
- Drospirenone and ethinyl estradiol and levomefolate
- Ethinyl estradiol and etonogestrel
- Ethinyl estradiol and ferrous bisglycinate and levonorgestrel
- Ethinyl estradiol and ferrous fumarate and levonorgestrel
- Ethinyl estradiol and ferrous fumarate and norethindrone
- Ethinyl estradiol and levonorgestrel
- Ethinyl estradiol and norelgestromin
- Ethinyl estradiol and norethindrone
- Ethinyl estradiol and norgestimate
- Ethinyl estradiol and segesterone
- Multiple vitamins
- Sodium iodide i 131
Source: FDA drug label (Ascor), McGuff Pharmaceuticals, Inc., effective May 29, 2026 (SPL set 388aad52-fc01-4784-9791-1dbc80c69306), via openFDA; the full label on DailyMed
What do FAERS reports show for ascorbic acid?
The FDA Adverse Event Reporting System holds 23,122 reports that list ascorbic acid among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 2,611 are coded as a death and 9,238 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.
Reports received each year
The most reported reactions
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026
What next?
- Other vitamin cs
- the pharmacologic class, with prices and generics
- Ascorbic acid side effects
- the label's list beside FAERS reports
- Check an interaction
- what two or more labels say about each other