Alternatives to apremilast
1 same-class SPL records vs apremilast - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.
Brand: Otezla
How to read a high-report FAERS peer set
apremilast ranks in the upper FAERS-volume third of the corpus (#45 of 524); 1 same-class peers are listed for field comparison only. Labeled indication field for apremilast: Apremilast is used to treat active psoriatic arthritis in adults and children 6 years and older.
Top FAERS reaction fields for apremilast total 125,731 reports across 10 reactions, set beside roflumilast. Counts are exposure-weighted submissions, not per-patient risk.
About apremilast
Apremilast (Otezla/Otezla XR) is a medicine that can help adults and children manage psoriatic arthritis and psoriasis. It can also help adults with oral ulcers from Behçet's Disease.
Used for: Apremilast is used to treat active psoriatic arthritis in adults and children 6 years and older. It also treats plaque psoriasis in adults and children 6 years and older who may use light therapy or other medicines that affect the whole body. Apremilast can also treat oral ulcers caused by Behçet's Disease in adults.
1 PDE4 Inhibitor peers (wide set)
apremilast vs roflumilast · FAERS reaction fields
FAERS top-reaction field "Diarrhoea" shows the widest count spread between apremilast and roflumilast in this extract (23,748-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | apremilast | roflumilast |
|---|---|---|
| Diarrhoea | 24,315 | 567 |
| Nausea | 21,927 | 465 |
| Psoriasis | 20,247 | - |
| Headache | 17,679 | 404 |
| Abdominal Discomfort | 8,065 | - |
| Psoriatic Arthropathy | 7,852 | - |
| Pain | 6,595 | - |
| Rash | 6,479 | - |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
apremilast FAERS volume vs class peers
FAERS volume band
apremilast is FAERS corpus rank #45 of 524 (high volume tercile). Top-reaction field total: 125,731.
Frequently Asked Questions
Where does apremilast sit in FAERS report volume vs PDE4 Inhibitor peers? ▼
Registry note: FAERS counts are voluntary reports and do not establish causation or risk rates. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for apremilast: see also the generic vs brand label guide when reading Otezla SPL strings.
Read our methodology - how this data is sourced, computed, and verified.