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Active Shortage Injection Other

Hydroxocobalamin Injection

Brand: CYANOKIT

This drug is currently listed as in shortage by the FDA. Affected manufacturer: BTG International Inc..

Active FDA Drug Shortage

Contact your pharmacist if you are affected. They can check availability from other manufacturers or suggest alternatives.

Shortage Details

Generic Name
Hydroxocobalamin Injection
Manufacturer
BTG International Inc.
Dosage Form
Injection
Presentation
Cyanokit, Injection, 5 g/250mL (NDC 50633-310-11)
Package NDC
50633-310-11

Status & Timeline

Status
Active Shortage
Availability
Limited Availability
First Reported
Nov 4, 2024
Last Updated
Oct 31, 2025
Therapeutic Category
Other

Shortage Reason

Cyanokit is available to order. To address the drug shortage, BTG International Inc (a SERB Pharmaceuticals company) coordinated with the U.S. Food and Drug Administration (FDA) to make the following impacted batches available to U.S. patients during this period of shortage.

Nearby — Other Hydroxocobalamin Shortage Records

Hydroxocobalamin Injection

Teva Pharmaceuticals USA, Inc.

Injection

Active Shortage

Frequently Asked Questions

Why is Hydroxocobalamin in shortage?
According to FDA data: Cyanokit is available to order. To address the drug shortage, BTG International Inc (a SERB Pharmaceuticals company) coordinated with the U.S. Food and Drug Administration (FDA) to make the following impacted batches available to U.S. patients during this period of shortage.
What can I do if my medication is in shortage?
Contact your pharmacist — they can check availability across suppliers or suggest an equivalent from a different manufacturer. Your prescriber may also recommend a therapeutic substitute from the same drug class.
How often is this data updated?
Shortage data comes from the FDA Drug Shortages Database via openFDA. The database is updated regularly as manufacturers report changes to the FDA.

What This Hydroxocobalamin Shortage Record Means

The FDA Drug Shortages database lists this record for Hydroxocobalamin Injection (brand: CYANOKIT) from BTG International Inc. with a current status of Active Shortage. The affected dosage form is Injection, presented as Cyanokit, Injection, 5 g/250mL (NDC 50633-310-11). Shortages are tracked at the manufacturer and presentation level — other manufacturers or formulations of the same generic may remain available, which is why pharmacists often can source a working substitute even when one record is flagged.

This shortage was first reported on Nov 4, 2024 and was last updated Oct 31, 2025. The FDA cites the following reason: Cyanokit is available to order. There is 1 other current record in this database covering the same generic, which gives a fuller picture of how disruption is playing out across manufacturers and dosage forms.

A shortage listing is a supply-side signal, not a patient-level instruction. Access can vary dramatically by pharmacy, region, hospital system, and insurance formulary — local pharmacists have real-time visibility that a national database cannot provide. Therapeutic substitutes often exist in the same class, but switching decisions belong with your prescriber, who weighs efficacy, dosing conversion, interaction profile, and personal history. This page summarizes public FDA data for educational reference only and is not medical advice. If your medication is affected, contact your pharmacist and prescriber to plan an appropriate response.

Disclaimer: This information comes from the FDA Drug Shortages Database and is for educational purposes only. It is not medical advice. Do not stop or change any medication without consulting your healthcare provider or pharmacist. Shortage status can change rapidly — always verify current availability with your pharmacist.

← All Drug Shortages

Sources: FDA Drug Shortages Database; openFDA API.

Read our methodology — how this data is sourced, computed, and verified.