Theophylline · more major-labeled pairs than Allopurinol
SPL labels Theophylline + Allopurinol as minor; Theophylline 54 / Allopurinol 6 in that band.
Mechanism on file: Taking high doses of allopurinol can make it harder for the body to get rid of theophylline. This can lead to higher levels of theophylline in your system.
FDA SPL severity: Minor
Theophylline + Allopurinol · SPL mechanism field
Taking high doses of allopurinol can make it harder for the body to get rid of theophylline. This can lead to higher levels of theophylline in your system.
Minor band excerpt · Theophylline with Allopurinol
Theophylline Clinical Impact Concomitant use of allopurinol doses greater than or equal to 600 mg/day may decrease the clearance of theophylline. Intervention Monitor and adjust theophylline doses as reflected in the prescribing information.
Theophylline · 27 major-labeled pairs (vs Allopurinol's 1)
- Adalimumab minor
- Adenosine minor
- Albendazole minor
- Alosetron minor
Allopurinol · 6 minor + 10 total pairs
- Ampicillin/Sulbactam minor
- Famciclovir minor
- Prazosin minor
- Terazosin minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.