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selenium

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Brand names: Selenium

Mineral Supplement OTC

Selenium is a mineral supplement. It provides selenium, an essential nutrient, to your body.

Drug Pricing (NADAC)

Generic Price

$0.21/unit

Generic Available

Yes (1 manufacturer)

Pricing data from NADAC (CMS), effective December 18, 2024. Compare all drug costs →

What it does

This medicine is a mineral supplement.

Common side effects

Tiredness, Headache, Diarrhea

Key warnings

There are no boxed warnings for this supplement.

How It Works

Selenium provides your body with selenium. Selenium is important for many bodily functions. It helps protect cells from damage and supports a healthy immune system.

How to Take It

Turn the tube upside down and twist the cap to open it. Use the clear cap to place 3 pellets under your tongue. Let the pellets dissolve 3 times a day or as needed. Take this medicine separately from food and drinks.

Pregnancy & Breastfeeding

It is not known if selenium is safe to use during pregnancy or while breastfeeding. Talk to your doctor before using this supplement if you are pregnant or breastfeeding.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

Storage

Store this medicine at room temperature, away from heat and moisture.

Side Effects (from patient reports)

Based on 2,811 FDA adverse event reports.

Tiredness
467
Headache
326
Diarrhea
308
Nausea
303
Pain
280
Joint pain
257
Dizziness
249
Medicine not working
234
Difficulty breathing
198
Trouble sleeping
189

FDA Adverse Event Report Analysis

Detailed analysis of 4,079 reports from the FDA Adverse Event Reporting System (FAERS). Reports span 2005–2025.

Total Reports

4,079

Death-Related Reports

236

Hospitalization Reports

1,077

Top Indication

Product Used For Unknown Indication

Gender Distribution

Female 2,483 (65%)
Male 1,333 (35%)

Age Distribution

0–17 77
18–44 349
45–64 970
65–74 693
75+ 517

Most Reported Adverse Reactions (FAERS)

# Reaction Reports
1 FATIGUE 467
2 HEADACHE 326
3 DIARRHOEA 308
4 NAUSEA 303
5 PAIN 280
6 ARTHRALGIA 257
7 DIZZINESS 250
8 DRUG INEFFECTIVE 234
9 DYSPNOEA 198
10 INSOMNIA 189
11 PAIN IN EXTREMITY 182
12 MUSCLE SPASMS 175
13 OFF LABEL USE 175
14 ANXIETY 174
15 WEIGHT DECREASED 170

Reactions in Death Reports

DEATH 113
DYSPNOEA 18
PNEUMONIA 17
FATIGUE 16
VOMITING 16
CONFUSIONAL STATE 15
ASTHENIA 14
ASCITES 13
SEIZURE 13
SEPSIS 13

Reactions in Hospitalization Reports

FATIGUE 123
NAUSEA 98
DIARRHOEA 94
PNEUMONIA 88
HEADACHE 79
DYSPNOEA 77
DIZZINESS 76
FALL 73
PAIN 71
PYREXIA 69

Source: FDA FAERS (Adverse Event Reporting System) FDA FAERS (Adverse Event Reporting System) Reports are voluntary and do not establish causation

Serious Warnings

There are no boxed warnings for this supplement.

Known Drug Interactions

7 DRUG INTERACTIONS Avoid coadministration of XOFLUZA with dairy products, calcium-fortified beverages, polyvalent cation-containing laxatives, antacids, or oral supplements (e.g., calcium, iron, magnesium, selenium, or zinc). Avoid coadministration of XOFLUZA with dairy products, calcium-fortified beverages, polyvalent cation-containing laxatives, antacids, or oral supplements (e.g., calcium, iron, magnesium, selenium, or zinc).

Mechanism: Selenium can attach to the medicine in your digestive system and stop it from getting into your bloodstream. This prevents the drug from working correctly.

What to do: Avoid taking selenium supplements at the same time as this medication. Talk to your doctor about when it is safe to take your supplements.

Common Questions

What is selenium?
Selenium is a mineral supplement.
How many pellets should I take?
Take 3 pellets under your tongue 3 times a day or as needed.
Can I take this with food?
No, take this medicine separately from food and drinks.
What should I do if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose.
How should I store this medicine?
Store this medicine at room temperature, away from heat and moisture.
Can I touch the pellets with my fingers?
To keep the pellets pure, avoid touching them with your fingers.
What do I do if the medicine doesn't seem to be working?
Talk to your doctor if you feel the medicine is not working.
Can I take this while pregnant?
Talk to your doctor before using this supplement if you are pregnant.
Can I take this while breastfeeding?
Talk to your doctor before using this supplement if you are breastfeeding.
What do I do if I get side effects?
Talk to your doctor if you get side effects that bother you.
What are the common side effects of selenium?
The most commonly reported side effects of selenium include Tiredness, Headache, Diarrhea, Nausea, Pain. Based on 2,811 FDA adverse event reports. Always consult your healthcare provider about potential side effects.
Does selenium interact with other medications?
Yes, selenium has 1 known drug interactions. Notable interactions include baloxavir marboxil. Always inform your doctor about all medications you are taking.
What drug class is selenium?
selenium belongs to the Mineral Supplement drug class. It is available over the counter (OTC). This medicine is a mineral supplement.
Is selenium safe during pregnancy?
It is not known if selenium is safe to use during pregnancy or while breastfeeding. Talk to your doctor before using this supplement if you are pregnant or breastfeeding. Always consult your healthcare provider before using any medication during pregnancy or breastfeeding.

Related Medications in Mineral Supplement

Other drugs grouped near selenium — same-class peers and common alternatives.

Compare selenium vs ascorbic acid side-by-side →

Medication Guides

Related Health & Safety Data

What the FDA Data Shows for selenium

The FDA label for selenium (sold under brand names such as Selenium) classifies it as an over-the-counter product in the Mineral Supplement class. This medicine is a mineral supplement. Official labeling lists 7 commonly reported side effects, including Tiredness, Headache, Diarrhea.

Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. For this drug, FAERS contains 2,811 voluntary reports. The database also lists 1 documented drug interaction derived from FDA labeling, with the top-flagged interaction rated moderate severity. NADAC pricing from CMS shows a generic unit cost of $0.21.

Report counts do not establish causation — a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information further shape supply and switching decisions. This page summarizes public FDA data for educational purposes only and is not a substitute for professional medical advice — always consult a licensed healthcare provider before starting, stopping, or changing any medication.

Data Sources

Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS). Pricing: CMS National Average Drug Acquisition Cost (NADAC).

FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. Always consult a healthcare professional before making medication decisions.

Last updated: December 31, 2018

All federal data sources used on this page