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progesterone vs theophylline

Side-by-side comparison of progesterone and theophylline. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

major Known Drug Interaction

The effect of progesterone on theophylline clearance is unknown. albuterol, systemic and inhaled mebendazole amoxicillin medroxyprogesterone ampicillin, with or without sulbactam methylprednisolone atenolol metronidazole azithromycin metoprolol caffeine, dietary ingestion nadolol cefaclor nifedipine co-trimoxazole (trimethoprim and sulfamethoxazole) nizatidine diltiazem norfloxacin dirithromycin ofloxacin enflurane omeprazole famotidine prednisone, prednisolone felodipine ranitidine finasteride rifabutin hydrocortisone roxithromycin isoflurane Sorbitol (purgative doses do not inhibit...

Recommendation: Tell your doctor if you start or stop taking hormone therapy. They may need to check your blood levels to make sure your theophylline dose is still safe and effective.

Drug Class
progesterone Progestogen Hormone
theophylline Methylxanthine Bronchodilator
Type
progesterone Prescription
theophylline Prescription
Summary
progesterone

Progesterone capsules contain a hormone that helps regulate your menstrual cycle and supports pregnancy. It is also used to prevent overgrowth of the uterine lining in women taking estrogen after menopause.

theophylline

Theophylline is a medicine that helps you breathe easier. It treats the symptoms of asthma and other lung problems.

What It Treats
progesterone

Progesterone capsules are used to prevent the lining of the uterus from growing too much in women who have gone through menopause and are taking estrogen. This medicine is also used to restart menstrual periods that have stopped in women who are not pregnant or going through menopause. This condition is called secondary amenorrhea.

theophylline

Theophylline treats the symptoms of long-term asthma and other lung diseases. These include emphysema and chronic bronchitis, which make it hard to breathe. This medicine helps to open up your airways so you can breathe easier.

How It Works
progesterone

Progesterone is a hormone naturally produced by your body. This medicine works by increasing progesterone levels in your body. This helps to regulate your menstrual cycle and protect the uterus.

theophylline

Theophylline is a bronchodilator. It works by relaxing the muscles in your airways. This allows more air to flow in and out of your lungs.

Common Side Effects
progesterone
  • Headache
  • Breast tenderness
  • Joint pain
  • Depression
  • Dizziness
theophylline
  • Nausea
  • Vomiting
  • Headache
  • Trouble sleeping (insomnia)
FAERS Reports
progesterone
  • Headache 1,946
  • Tiredness 1,673
  • Pain 1,369
  • Feeling sick to your stomach 1,362
  • Skin rash 903
theophylline
  • Difficulty breathing 2,273
  • Asthma 1,942
  • Pneumonia 1,317
  • Wheezing 1,306
  • Vomiting 1,101
Serious Warnings
progesterone

Estrogen plus progestin therapy should not be used to prevent heart disease or dementia. Estrogen plus progestin may increase your risk of blood clots, stroke, heart attack, breast cancer, and dementia. Progesterone with estrogens should be prescribed at the lowest effective doses and for the shortest duration.

theophylline

If your theophylline levels get too high in your blood, it can cause serious side effects. These include severe vomiting, irregular heartbeats, and seizures. These can be life-threatening.

Pregnancy
progesterone

You should not take progesterone capsules if you are pregnant or think you might be pregnant. Talk to your doctor if you become pregnant while taking this medicine. It is not known if progesterone passes into breast milk. Talk to your doctor about the risks and benefits of breastfeeding while taking this medicine.

theophylline

It is not known if theophylline can harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is also not known if theophylline passes into breast milk, so talk to your doctor if you are breastfeeding.

How to Read This progesterone vs theophylline Comparison

progesterone is classified in the Progestogen Hormone drug class, while theophylline sits within the Methylxanthine Bronchodilator class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, progesterone has 7,253 submissions while theophylline has 7,939. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known major interaction flagged in FDA labeling, attributed to it is not fully known how progesterone affects theophylline, but it may change how quickly your body clears the drug. this could lead to theophylline levels being higher or lower than expected.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between progesterone and theophylline - always consult your physician or pharmacist first.

Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.