metformin vs miglitol
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Side-by-side comparison of metformin and miglitol. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
The effect of miglitol (100 mg 3 times daily for 7 days) on the pharmacokinetics of a single 1000 mg dose of metformin was investigated in healthy volunteers. Mean AUC and C max values for metformin were 12% to 13% lower when the volunteers were given miglitol as compared with placebo, but this difference was not statistically significant.
No summary available.
Miglitol (Glyset) helps control blood sugar in adults with type 2 diabetes. It should be used with diet and exercise.
Information not available.
Miglitol treats type 2 diabetes. It helps lower your blood sugar levels after meals. You should use it along with a healthy diet and regular exercise to manage your diabetes.
Information not available.
Miglitol slows down the digestion of carbohydrates. This helps to prevent a large rise in blood sugar after you eat. It works in your gut to block certain enzymes.
- • Diarrhea
- • Upper respiratory tract infection (like a cold)
- • Headache
- • Gas
- • Diarrhea
- • Abdominal pain
- Nausea 21,946
- Diarrhoea 21,884
- Blood Glucose Increased 18,328
- Fatigue 17,252
- Acute Kidney Injury 16,440
- Hypoglycaemia 67
- Hepatic Function Abnormal 46
- Decreased Appetite 39
- Diarrhoea 37
- Renal Impairment 37
No specific warnings noted.
No specific warnings noted.
No pregnancy information available.
There is not enough information about the safety of miglitol during pregnancy or breastfeeding. Talk to your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
Also Compare, Nearby Drugs
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How to Read This metformin vs miglitol Comparison
metformin is classified in the Biguanide drug class, while miglitol sits within the Alpha-Glucosidase Inhibitor class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, metformin has 95,850 submissions while miglitol has 226. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to miglitol may slightly lower the amount of metformin that enters your bloodstream, but the change is usually not large enough to matter.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for metformin or miglitol.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.