fosinopril vs moexipril

PlainMeds reviewed this comparison against our methodology in August 2026. It places FDA and CMS record fields side by side, without recommending either medication.

Side-by-side comparison of fosinopril and moexipril. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

Drug Class
fosinopril ACE Inhibitor
moexipril ACE Inhibitor
Type
fosinopril Prescription
moexipril Prescription
Summary
fosinopril

Fosinopril is a medicine that lowers blood pressure. It can also help manage heart failure.

moexipril

Moexipril is a medicine used to treat high blood pressure. It can be used alone or with a water pill.

What It Treats
fosinopril

Fosinopril is used to treat high blood pressure. It can be used alone or with a water pill (diuretic). Fosinopril also helps manage heart failure when used with other medicines.

moexipril

Moexipril is used to treat high blood pressure. High blood pressure can harm your heart, brain, and kidneys. Lowering your blood pressure can help prevent heart attacks and strokes. This medicine can be used by itself or with other medicines to lower blood pressure.

How It Works
fosinopril

Fosinopril belongs to a class of drugs called ACE inhibitors. It works by blocking a substance in your body that tightens blood vessels. This helps your blood vessels relax and lowers your blood pressure.

moexipril

Moexipril belongs to a class of drugs called ACE inhibitors. It works by blocking a substance in your body that tightens blood vessels. This helps your blood vessels relax and widens them, which lowers your blood pressure.

Common Side Effects
fosinopril
  • Cough
  • Dizziness
  • Nausea
  • Vomiting
moexipril
  • Cough
  • Dizziness
  • Diarrhea
  • Flu-like symptoms
  • Fatigue
FAERS Reports
fosinopril
  • Fatigue 239
  • Diarrhoea 232
  • Dyspnoea 210
  • Nausea 204
  • Dizziness 179
moexipril
  • Asthenia 8
  • Dyspnoea 6
  • Nausea 5
  • Blood Pressure Decreased 4
  • Cerebrovascular Accident 4
Serious Warnings
fosinopril

Fosinopril can harm your unborn baby, even causing death. Stop taking fosinopril as soon as you know you are pregnant.

moexipril

This medicine can harm your unborn baby. If you are pregnant or plan to become pregnant, tell your doctor right away. Stop taking moexipril as soon as you know you are pregnant.

Pregnancy
fosinopril

Do not take fosinopril if you are pregnant. It can cause serious harm or death to your unborn baby. Talk to your doctor about other blood pressure medicines if you are breastfeeding.

moexipril

Moexipril can cause injury or death to a developing fetus. If you become pregnant while taking this medicine, stop taking it immediately and tell your doctor. It is not known if moexipril passes into breast milk, so talk to your doctor before breastfeeding.

Also Compare, Nearby Drugs

How to Read This fosinopril vs moexipril Comparison

fosinopril is classified in the ACE Inhibitor drug class, while moexipril sits within the ACE Inhibitor class. Because both drugs share the same classification, they are often considered interchangeable in theory, but clinical outcomes rarely track that cleanly. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, fosinopril has 1,064 submissions while moexipril has 27. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. No direct interaction between these two drugs is listed in our FDA-derived dataset, though co-prescription still warrants pharmacist review. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for fosinopril or moexipril.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.