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eprosartan vs hydrochlorothiazide

Side-by-side comparison of eprosartan and hydrochlorothiazide. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

or 800 mg q.d.) doses have been safely used concomitantly with a thiazide diuretic (hydrochlorothiazide).

Recommendation: No special changes are usually needed, but you should still follow your doctor's instructions for blood pressure monitoring.

Drug Class
eprosartan Angiotensin II Receptor Blocker (ARB)
hydrochlorothiazide Thiazide Diuretic
Type
eprosartan Prescription
hydrochlorothiazide Prescription
Summary
eprosartan

Eprosartan (Teveten) is a medicine that lowers high blood pressure. It can be used alone or with other blood pressure medicines.

hydrochlorothiazide

No summary available.

What It Treats
eprosartan

Eprosartan is used to treat high blood pressure (hypertension). It can be used by itself or with other medicines to lower your blood pressure. Lowering blood pressure helps prevent strokes, heart attacks, and kidney problems.

hydrochlorothiazide

Information not available.

How It Works
eprosartan

Eprosartan belongs to a class of drugs called angiotensin II receptor blockers (ARBs). It works by blocking a substance in your body that tightens blood vessels. This helps blood vessels relax, which lowers blood pressure.

hydrochlorothiazide

Information not available.

Common Side Effects
eprosartan
  • Viral infection
  • Injury
  • Fatigue
  • Abdominal pain
  • Joint pain
hydrochlorothiazide
  • Dizziness
  • Headache
  • Cough
  • Fatigue
FAERS Reports
eprosartan

No adverse event reports.

hydrochlorothiazide
  • Tiredness 10,013
  • Feeling sick to your stomach 9,706
  • Loose stools 8,311
  • Discomfort 7,665
  • Difficulty breathing 7,584
Serious Warnings
eprosartan

If you become pregnant, stop taking eprosartan right away. This medicine can cause serious harm or death to your unborn baby.

hydrochlorothiazide

No specific warnings noted.

Pregnancy
eprosartan

Eprosartan can harm your unborn baby, even causing death. Stop taking this medicine as soon as you know you are pregnant. It is not known if eprosartan passes into breast milk, so talk to your doctor about the best way to feed your baby if you are taking this medicine.

hydrochlorothiazide

No pregnancy information available.

Also Compare, Nearby Drugs

How to Read This eprosartan vs hydrochlorothiazide Comparison

eprosartan is classified in the Angiotensin II Receptor Blocker (ARB) drug class, while hydrochlorothiazide sits within the Thiazide Diuretic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, eprosartan has 0 submissions while hydrochlorothiazide has 43,279. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to these two drugs work together to lower blood pressure and have been shown to be safe when used at the same time.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between eprosartan and hydrochlorothiazide - always consult your physician or pharmacist first.

Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.