enoxaparin vs ketorolac
Side-by-side comparison of enoxaparin and ketorolac. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
These agents include medications such as: anticoagulants, platelet inhibitors including acetylsalicylic acid, salicylates, NSAIDs (including ketorolac tromethamine), dipyridamole, or sulfinpyrazone.
Recommendation: Use this combination with caution and tell your doctor immediately if you notice any unusual bruising or bleeding.
Lovenox
Toradol
Enoxaparin (Lovenox) is a type of blood thinner. It helps prevent and treat blood clots.
Ketorolac (Toradol) is a strong pain reliever. It is a nonsteroidal anti-inflammatory drug (NSAID).
This medicine can prevent blood clots from forming after surgery or during illness when you are not moving around much. It also treats blood clots in your veins, with or without a pulmonary embolism (a blood clot in the lungs). Enoxaparin can also help prevent chest pain and heart attacks.
Ketorolac is used for short-term relief of moderate to severe pain. It is often used after surgery. You should only use it for up to 5 days.
Enoxaparin works by blocking certain proteins in your blood that help clots form. This helps to prevent new clots from forming and keeps existing clots from getting bigger. It makes your blood less likely to clot.
Ketorolac reduces pain by blocking the production of substances called prostaglandins in the body. Prostaglandins contribute to inflammation and pain. By reducing prostaglandins, ketorolac helps to alleviate pain.
- • Bleeding
- • Low red blood cell count (anemia)
- • Low platelet count (thrombocytopenia)
- • Increased liver enzymes
- • Diarrhea
- • Stomach pain
- • Constipation or diarrhea
- • Upset stomach
- • Gas
- • Feeling full
- Shortness of breath 2,369
- Feeling sick to your stomach 2,353
- Loose or watery stools 2,244
- Low red blood cell count 2,190
- Low platelet count 2,066
No adverse event reports.
Enoxaparin can cause bleeding around your spine if you get an epidural or spinal tap. This can lead to long-term or permanent paralysis. Tell your doctor if you are taking other medicines that can increase bleeding, like NSAIDs (such as ibuprofen) or aspirin. Your doctor will monitor you for signs of nerve problems.
Ketorolac can cause stomach ulcers, bleeding, and holes in the stomach or intestines, which can be fatal. It can increase your risk of heart attack or stroke, which can be fatal. Ketorolac is not for long-term use or for treating minor pain. Do not take it before major surgery. It can also cause kidney problems and bleeding problems.
Tell your doctor if you are pregnant or plan to become pregnant. Enoxaparin may not be safe for your baby. Discuss the risks and benefits with your doctor.
Ketorolac may harm your unborn baby. Do not use ketorolac during labor and delivery. Talk to your doctor if you are pregnant or breastfeeding.
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How to Read This enoxaparin vs ketorolac Comparison
enoxaparin is classified in the Low-Molecular-Weight Heparin drug class, while ketorolac sits within the Nonsteroidal Anti-Inflammatory Drug (NSAID) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, enoxaparin has 11,222 submissions while ketorolac has 0. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to both drugs affect how your blood clots, and taking them together increases your risk of serious bleeding.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between enoxaparin and ketorolac - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.