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clarithromycin vs saxagliptin

Side-by-side comparison of clarithromycin and saxagliptin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

Similar significant increases in plasma concentrations of saxagliptin are anticipated with other strong CYP3A4/5 inhibitors (e.g., atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, ritonavir, saquinavir, and telithromycin).

Recommendation: Your doctor may need to adjust your dose or watch you more closely for side effects while taking both drugs.

Drug Class
clarithromycin Macrolide Antibiotic
saxagliptin DPP-4 Inhibitor
Type
clarithromycin Prescription
saxagliptin Prescription
Summary
clarithromycin

Clarithromycin is an antibiotic that fights bacterial infections. It belongs to a class of drugs called macrolides.

saxagliptin

No summary available.

What It Treats
clarithromycin

Clarithromycin treats mild to moderate infections caused by certain bacteria. It can treat bronchitis, sinus infections, pneumonia, and throat/tonsil infections. It also treats skin infections, ear infections in children, certain mycobacterial infections, and H. pylori infections that cause ulcers.

saxagliptin

Information not available.

How It Works
clarithromycin

Clarithromycin works by stopping the growth of bacteria. It prevents bacteria from making proteins they need to survive. This helps your body fight off the infection.

saxagliptin

Information not available.

Common Side Effects
clarithromycin
  • Abdominal pain
  • Diarrhea
  • Nausea
  • Vomiting
  • Taste changes
saxagliptin
  • Upper respiratory tract infection
  • Urinary tract infection
  • High cholesterol
FAERS Reports
clarithromycin
  • Drug Interaction 2,906
  • Nausea 2,214
  • Dyspnoea 1,959
  • Diarrhoea 1,937
  • Malaise 1,650
saxagliptin
  • Congestive heart failure 428
  • Increased blood sugar 401
  • Heart failure 400
  • Feeling sick to your stomach 372
  • Loose stools 328
Serious Warnings
clarithromycin

Clarithromycin can cause severe allergic reactions. Stop taking it and get medical help right away if you have signs of a reaction. This medicine can also cause heart rhythm problems (QT prolongation) and liver problems. Tell your doctor if you have heart or liver issues. Clarithromycin may increase the risk of death in patients with coronary artery disease.

saxagliptin

No specific warnings noted.

Pregnancy
clarithromycin

Clarithromycin is not recommended during pregnancy unless there are no other options. Talk to your doctor if you are pregnant or plan to become pregnant. It is not known if clarithromycin passes into breast milk, so talk to your doctor before breastfeeding.

saxagliptin

No pregnancy information available.

Also Compare, Nearby Drugs

How to Read This clarithromycin vs saxagliptin Comparison

clarithromycin is classified in the Macrolide Antibiotic drug class, while saxagliptin sits within the DPP-4 Inhibitor class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, clarithromycin has 10,666 submissions while saxagliptin has 1,929. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to clarithromycin stops the body from breaking down saxagliptin, which can lead to higher levels of the drug in your system.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between clarithromycin and saxagliptin - always consult your physician or pharmacist first.

Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.