clarithromycin vs lurasidone
Side-by-side comparison of clarithromycin and lurasidone. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
major Known Drug Interaction
Colchicine (in patients with normal renal and hepatic function) Use With Caution Antipsychotics: Pimozide Contraindicated Pimozide: [See Contraindications ( 4.2 )] Quetiapine Lurasidone Quetiapine: Quetiapine is a substrate for CYP3A4, which is inhibited by clarithromycin. Lurasidone: [See Contraindications ( 4.7 )] Antispasmodics: Tolterodine (patients deficient in CYP2D6 activity) Use With Caution Tolterodine: The primary route of metabolism for tolterodine is via CYP2D6.
Recommendation: Avoid taking these two drugs together as this combination is not recommended by the FDA.
Biaxin
Latuda
Clarithromycin is an antibiotic that fights bacterial infections. It belongs to a class of drugs called macrolides.
Lurasidone (Latuda) is a medicine used to treat schizophrenia and bipolar depression. It helps to balance chemicals in the brain.
Clarithromycin treats mild to moderate infections caused by certain bacteria. It can treat bronchitis, sinus infections, pneumonia, and throat/tonsil infections. It also treats skin infections, ear infections in children, certain mycobacterial infections, and H. pylori infections that cause ulcers.
Lurasidone is used to treat schizophrenia in adults and teens ages 13-17. It also treats the depressive phase of bipolar disorder in adults and children ages 10-17. In adults, it can be used alone or with lithium or valproate for bipolar depression.
Clarithromycin works by stopping the growth of bacteria. It prevents bacteria from making proteins they need to survive. This helps your body fight off the infection.
Lurasidone is an atypical antipsychotic. It works by affecting certain chemicals in the brain, such as dopamine and serotonin. This helps to improve mood, thinking, and behavior.
- • Abdominal pain
- • Diarrhea
- • Nausea
- • Vomiting
- • Taste changes
- • Feeling sleepy
- • Feeling restless and needing to move
- • Nausea
- • Weight gain
- • Trouble sleeping
- Drug Interaction 2,906
- Nausea 2,214
- Dyspnoea 1,959
- Diarrhoea 1,937
- Malaise 1,650
- Feeling worried or nervous 1,223
- Feeling strange or not like yourself 1,166
- Feeling sad or hopeless 1,120
- Gaining weight 1,077
- Feeling sleepy 1,066
Clarithromycin can cause severe allergic reactions. Stop taking it and get medical help right away if you have signs of a reaction. This medicine can also cause heart rhythm problems (QT prolongation) and liver problems. Tell your doctor if you have heart or liver issues. Clarithromycin may increase the risk of death in patients with coronary artery disease.
This medicine has two important warnings: * **Increased risk of death in elderly people with dementia:** If you are an older adult with dementia-related psychosis, this medicine may increase your chance of death. Lurasidone is not approved for this condition. * **Increased risk of suicidal thoughts and behaviors:** Antidepressants may increase the risk of suicidal thoughts and behaviors in children, teens, and young adults. Your doctor will need to watch you closely for worsening mood or suicidal thoughts.
Clarithromycin is not recommended during pregnancy unless there are no other options. Talk to your doctor if you are pregnant or plan to become pregnant. It is not known if clarithromycin passes into breast milk, so talk to your doctor before breastfeeding.
Tell your doctor if you are pregnant or plan to become pregnant. Babies born to mothers who take this medicine in the last 3 months of pregnancy may have withdrawal symptoms or other problems after birth. Talk to your doctor about the risks and benefits of taking lurasidone during pregnancy.
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How to Read This clarithromycin vs lurasidone Comparison
clarithromycin is classified in the Macrolide Antibiotic drug class, while lurasidone sits within the Atypical Antipsychotic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, clarithromycin has 10,666 submissions while lurasidone has 5,652. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known major interaction flagged in FDA labeling, attributed to clarithromycin stops the body from clearing lurasidone by blocking a specific enzyme, which can lead to toxic levels of the medication.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between clarithromycin and lurasidone - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.