chloroquine vs methylprednisolone
Side-by-side comparison of chloroquine and methylprednisolone. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, isofamide, rasburicase Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine...
Recommendation: Your doctor should monitor you for signs of low oxygen, such as blue-tinted skin or shortness of breath. They may need to perform blood tests to ensure your safety.
Aralen
Medrol
Chloroquine phosphate is a drug used to treat and prevent malaria. It can also treat a type of infection called extraintestinal amebiasis.
Methylprednisolone (Medrol) is a corticosteroid medicine. It reduces inflammation and affects the immune system.
This medicine can treat uncomplicated malaria caused by certain types of parasites. It can also prevent malaria in areas where the parasites are sensitive to chloroquine. Chloroquine can also treat extraintestinal amebiasis, which is an infection outside of the intestines. This medicine will not prevent malaria from returning in some patients.
This medicine can treat many conditions. It can help with allergies, skin problems, and hormone imbalances. It can also help with gut and blood disorders.
Chloroquine phosphate works by killing the parasites that cause malaria and amebiasis. It stops the parasites from growing and multiplying in your body. For malaria caused by certain parasites, you may need to take another medicine with chloroquine.
Methylprednisolone reduces inflammation in the body. It also changes how your immune system works. This can help control symptoms of different diseases.
No common side effects listed.
No common side effects listed.
- Throwing up 49
- Feeling sick to your stomach 48
- Head pain 41
- High blood pressure 41
- Lung infection 40
- Feeling very tired 7,792
- Aching or soreness 7,273
- Feeling sick to your stomach 7,212
- Pain in your head 7,058
- Fever 6,883
You should not take this medicine if you have changes in your retina or vision. You should not take this medicine if you are allergic to similar drugs.
This medicine is not for injection into the spine. This can cause serious medical problems. Do not take this medicine if you have a fungal infection, unless it's a localized joint condition.
Talk to your doctor if you are pregnant or breastfeeding before taking this medicine. It is not known if chloroquine can harm your unborn baby. Chloroquine can pass into breast milk.
Tell your doctor if you are pregnant or plan to become pregnant. This medicine may harm your unborn baby. Talk to your doctor about the risks and benefits.
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How to Read This chloroquine vs methylprednisolone Comparison
chloroquine is classified in the Antimalarial drug class, while methylprednisolone sits within the Corticosteroid class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, chloroquine has 219 submissions while methylprednisolone has 36,218. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to chloroquine is known to cause a blood condition called methemoglobinemia, which makes it harder for your blood to carry oxygen. taking it with other medications may increase the risk of this blood disorder.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between chloroquine and methylprednisolone - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.