chloroquine vs lidocaine topical
Side-by-side comparison of chloroquine and lidocaine topical. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
moderate Known Drug Interaction
Drugs That May Cause Methemoglobinemia When Used with LIDODERM Patients who are administered local anesthetics are at increased risk of developing methemoglobinemia when concurrently exposed to the following drugs, which could include other local anesthetics: Examples of Drugs Associated with Methemoglobinemia : Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea,...
Recommendation: Use these drugs together only if your doctor says it is necessary and monitors you closely. Seek help immediately if your skin, lips, or fingernails look blue or gray.
Aralen
Lidoderm
Chloroquine phosphate is a drug used to treat and prevent malaria. It can also treat a type of infection called extraintestinal amebiasis.
Lidoderm is a skin patch that contains the numbing medicine lidocaine. It is used to relieve nerve pain after shingles.
This medicine can treat uncomplicated malaria caused by certain types of parasites. It can also prevent malaria in areas where the parasites are sensitive to chloroquine. Chloroquine can also treat extraintestinal amebiasis, which is an infection outside of the intestines. This medicine will not prevent malaria from returning in some patients.
Lidoderm is used to relieve pain caused by post-herpetic neuralgia. This is nerve pain that can happen after you have shingles. The patch should only be applied to skin that is not broken or irritated.
Chloroquine phosphate works by killing the parasites that cause malaria and amebiasis. It stops the parasites from growing and multiplying in your body. For malaria caused by certain parasites, you may need to take another medicine with chloroquine.
Lidoderm contains lidocaine, a local anesthetic. It works by numbing the area where you apply the patch. This reduces pain signals in that area.
No common side effects listed.
- • Blisters where you put the patch
- • Bruising where you put the patch
- • Burning feeling where you put the patch
- • Skin color changes where you put the patch
- • Skin irritation where you put the patch
- Throwing up 49
- Feeling sick to your stomach 48
- Head pain 41
- High blood pressure 41
- Lung infection 40
No adverse event reports.
You should not take this medicine if you have changes in your retina or vision. You should not take this medicine if you are allergic to similar drugs.
Using Lidoderm with certain drugs can increase the risk of a blood disorder called methemoglobinemia. Tell your doctor about all other medicines you take.
Talk to your doctor if you are pregnant or breastfeeding before taking this medicine. It is not known if chloroquine can harm your unborn baby. Chloroquine can pass into breast milk.
Tell your doctor if you are pregnant or breastfeeding before using Lidoderm. It is not known if Lidoderm can harm your unborn baby. It is also not known if Lidoderm passes into breast milk.
How to Read This chloroquine vs lidocaine topical Comparison
chloroquine is classified in the Antimalarial drug class, while lidocaine topical sits within the Topical Anesthetic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, chloroquine has 219 submissions while lidocaine topical has 0. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known moderate interaction flagged in FDA labeling, attributed to both drugs can interfere with how your blood carries oxygen, which can lead to a dangerous health issue. combining them makes this problem more likely to happen.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between chloroquine and lidocaine topical - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.