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Active Shortage Injection Cardiovascular

Conivaptan Hydrochloride Injection

This drug is currently listed as in shortage by the FDA. Affected manufacturer: Cumberland Pharmaceuticals Inc..

Active FDA Drug Shortage

Contact your pharmacist if you are affected. They can check availability from other manufacturers or suggest alternatives.

Shortage Details

Generic Name
Conivaptan Hydrochloride Injection
Manufacturer
Cumberland Pharmaceuticals Inc.
Dosage Form
Injection
Presentation
Vaprisol Dextrose In Plastic Container, Injection, 20 mg/100 mL (NDC 66220-160-10)
Package NDC
66220-160-10

Status & Timeline

Status
Active Shortage
Availability
Unavailable
First Reported
Mar 14, 2022
Last Updated
Mar 16, 2026
Therapeutic Category
Cardiovascular

Frequently Asked Questions

Why is Conivaptan in shortage?
Drug shortages can result from manufacturing problems, quality issues, raw material shortages, or increased demand. The FDA works with manufacturers to resolve shortages as quickly as possible.
What can I do if my medication is in shortage?
Contact your pharmacist — they can check availability across suppliers or suggest an equivalent from a different manufacturer. Your prescriber may also recommend a therapeutic substitute from the same drug class.
How often is this data updated?
Shortage data comes from the FDA Drug Shortages Database via openFDA. The database is updated regularly as manufacturers report changes to the FDA.

What This Conivaptan Shortage Record Means

The FDA Drug Shortages database lists this record for Conivaptan Hydrochloride Injection from Cumberland Pharmaceuticals Inc. with a current status of Active Shortage. The affected dosage form is Injection, presented as Vaprisol Dextrose In Plastic Container, Injection, 20 mg/100 mL (NDC 66220-160-10). Shortages are tracked at the manufacturer and presentation level — other manufacturers or formulations of the same generic may remain available, which is why pharmacists often can source a working substitute even when one record is flagged.

This shortage was first reported on Mar 14, 2022 and was last updated Mar 16, 2026. FDA-supplied reason codes are not recorded for this entry; common drivers include manufacturing quality issues, raw-material constraints, demand surges, and voluntary business decisions to discontinue a presentation. No other current shortage records match this generic in the database, which can signal that either the disruption is contained to one manufacturer or other suppliers have not yet formally reported a shortfall.

A shortage listing is a supply-side signal, not a patient-level instruction. Access can vary dramatically by pharmacy, region, hospital system, and insurance formulary — local pharmacists have real-time visibility that a national database cannot provide. Therapeutic substitutes often exist in the same class, but switching decisions belong with your prescriber, who weighs efficacy, dosing conversion, interaction profile, and personal history. This page summarizes public FDA data for educational reference only and is not medical advice. If your medication is affected, contact your pharmacist and prescriber to plan an appropriate response.

Disclaimer: This information comes from the FDA Drug Shortages Database and is for educational purposes only. It is not medical advice. Do not stop or change any medication without consulting your healthcare provider or pharmacist. Shortage status can change rapidly — always verify current availability with your pharmacist.